Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density

Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density

Abstract Rationale [11C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry program. Methods Sequential whole-bo...

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Bibliographic Details
Main Authors: Christopher Cawthorne, Paul Maguire, Joel Mercier, David Sciberras, Kim Serdons, Guy Bormans, Jan de Hoon, Koen Van Laere, Michel Koole
Format: Article
Language:English
Published: SpringerOpen 2021-04-01
Series:EJNMMI Physics
Subjects:
[11C]-UCB-J
Synaptic density
Radiation dosimetry
Human biodistribution
OLINDA
Online Access:https://doi.org/10.1186/s40658-021-00384-5

Internet

https://doi.org/10.1186/s40658-021-00384-5

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