Human biodistribution and dosimetry of [11C]-UCB-J, a PET radiotracer for imaging synaptic density
Abstract Rationale [11C]-UCB-J is an emerging tool for the noninvasive measurement of synaptic vesicle density in vivo. Here, we report human biodistribution and dosimetry estimates derived from sequential whole-body PET using two versions of the OLINDA dosimetry program. Methods Sequential whole-bo...
Main Authors: | Christopher Cawthorne, Paul Maguire, Joel Mercier, David Sciberras, Kim Serdons, Guy Bormans, Jan de Hoon, Koen Van Laere, Michel Koole |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2021-04-01
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Series: | EJNMMI Physics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40658-021-00384-5 |
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