MHC class II tetramers made from isolated recombinant α and β chains refolded with affinity-tagged peptides.

MHC class II tetramers made from isolated recombinant α and β chains refolded with affinity-tagged peptides.

Targeting CD4+ T cells through their unique antigen-specific, MHC class II-restricted T cell receptor makes MHC class II tetramers an attractive strategy to identify, validate and manipulate these cells at the single cell level. Currently, generating class II tetramers is a specialized undertaking e...

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Bibliographic Details
Main Authors: Peter Braendstrup, Sune Justesen, Thomas Osterbye, Lise Lotte Bruun Nielsen, Roberto Mallone, Lars Vindeløv, Anette Stryhn, Søren Buus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759463?pdf=render

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http://europepmc.org/articles/PMC3759463?pdf=render

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