Metformin paradoxically worsens insulin resistance in SHORT syndrome

Metformin paradoxically worsens insulin resistance in SHORT syndrome

Abstract Background SHORT syndrome is an autosomal dominant condition associated severe insulin resistance (IR) and lipoatrophy due to post-receptor defect in insulin signaling involving phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), where no clear treatment guidelines are available. Metho...

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Bibliographic Details
Main Authors: Krzysztof C. Lewandowski, Katarzyna Dąbrowska, Maria Brzozowska, Joanna Kawalec, Andrzej Lewiński
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Diabetology & Metabolic Syndrome
Subjects:
SHORT syndrome
Metformin
Insulin resistance
Online Access:http://link.springer.com/article/10.1186/s13098-019-0477-z

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http://link.springer.com/article/10.1186/s13098-019-0477-z

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