5-Azacytidine restores interleukin 6-increased production in mesenchymal stromal cells from myelodysplastic patients

Introduction: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological diseases. In addition to defects in hematologic progenitor and stem cells, dysfunctions in the bone marrow microenvironment (BMM) participate in the MDS pathogenesis. Furthermore, the immune response is d...

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Bibliographic Details
Main Authors: Matilde Boada, Lourdes Echarte, Cecilia Guillermo, Lilián Diaz, Cristina Touriño, Sofía Grille
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Hematology, Transfusion and Cell Therapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137920300043