In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

In vivo oxygen measurement in cerebrospinal fluid of pigs to determine physiologic and pathophysiologic oxygen values during CNS infections

Abstract During infection and inflammation, a reduced oxygen level clearly affects cellular functions. Oxygen levels during CNS infections are unknown. Here we established and evaluated an in vivo measurement system to characterize the oxygen level in parallel with bacterial numbers (CFU/mL), the ce...

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Bibliographic Details
Main Authors: Nicole de Buhr, Alexander Martens, Marita Meurer, Marta C. Bonilla, Franz Söbbeler, Lara Twele, Stephan Neudeck, Michael Wendt, Andreas Beineke, Sabine Kästner, Maren von Köckritz-Blickwede
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Neuroscience
Subjects:
Oxygen
Meningitis
Cerebrospinal fluid
Hypoxia
Physioxia
Normoxia
Online Access:https://doi.org/10.1186/s12868-021-00648-x

Internet

https://doi.org/10.1186/s12868-021-00648-x

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