PLASMID DESIGN FOR PRODUCTION OF CHIMERIC ANTIBODIES WITH DEFINED SPECIFICITY IN EUKARYOTES

PLASMID DESIGN FOR PRODUCTION OF CHIMERIC ANTIBODIES WITH DEFINED SPECIFICITY IN EUKARYOTES

Aim. In this study we aimed to design the universal genetic construction expressing the light and heavy chains of a chimeric antibody, to develop methodological approaches for the production of chimeric antibodies with defined specificity using the monoclonal antibodies to diphtheria toxin (DT) DT-1...

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Bibliographic Details
Main Authors: A. S. Oksanich, T. G. Samartseva, E. B. Faizjuloev, N. F. Gavrilova, I. V. Yakovleva, V. V. Sviridov, V. V. Zverev
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2017-12-01
Series: Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
«супервектор»
immunoglobulin genes
«supervector»
chimeric antibodies
diphtheria toxin
toxin neutralizing activity
Online Access:https://microbiol.elpub.ru/jour/article/view/231

Internet

https://microbiol.elpub.ru/jour/article/view/231

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