Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis.

Betaglycan (TβRIII) is expressed in the thymus and regulates T cell development by protecting thymocytes from apoptosis.

TGF-β type III receptor (TβRIII) is a coreceptor for TGFβ family members required for high-affinity binding of these ligands to their receptors, potentiating their cellular functions. TGF-β [1]-[3], bone morphogenetic proteins (BMP2/4) and inhibins regulate different checkpoints during T cell differ...

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Bibliographic Details
Main Authors: German R Aleman-Muench, Valentin Mendoza, Kaye Stenvers, Eduardo A Garcia-Zepeda, Fernando Lopez-Casillas, Chander Raman, Gloria Soldevila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3430661?pdf=render

Internet

http://europepmc.org/articles/PMC3430661?pdf=render

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