Genomic Analysis of Carbapenemase-Producing Extensively Drug-Resistant <i>Klebsiella pneumoniae</i> Isolates Reveals the Horizontal Spread of p18-43_01 Plasmid Encoding <i>bla</i><sub>NDM-1</sub> in South Africa

Genomic Analysis of Carbapenemase-Producing Extensively Drug-Resistant <i>Klebsiella pneumoniae</i> Isolates Reveals the Horizontal Spread of p18-43_01 Plasmid Encoding <i>bla</i><sub>NDM-1</sub> in South Africa

Whole-genome sequence (WGS) analyses were employed to investigate the genomic epidemiology of extensively drug-resistant <i>Klebsiella pneumoniae</i> strains, focusing on the carbapenem resistance-encoding determinants, mobile genetic support, clonal and epidemiological relationships. A...

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Bibliographic Details
Main Authors: Yogandree Ramsamy, Koleka P. Mlisana, Mushal Allam, Daniel G. Amoako, Akebe L. K. Abia, Arshad Ismail, Ravesh Singh, Theroshnie Kisten, Khine Swe Swe Han, David J. Jackson Muckart, Timothy Hardcastle, Moosa Suleman, Sabiha Y. Essack
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Microorganisms
Subjects:
genomics
carbapenemase
<i>klebsiella pneumoniae</i>
extensively drug-resistant
mobile genetic elements
epidemiology
phylogenomic
south africa
Online Access:https://www.mdpi.com/2076-2607/8/1/137

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https://www.mdpi.com/2076-2607/8/1/137

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