Assessing T cell clonal size distribution: a non-parametric approach.

Clonal structure of the human peripheral T-cell repertoire is shaped by a number of homeostatic mechanisms, including antigen presentation, cytokine and cell regulation. Its accurate tuning leads to a remarkable ability to combat pathogens in all their variety, while systemic failures may lead to se...

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Bibliographic Details
Main Authors: Olesya V Bolkhovskaya, Daniil Yu Zorin, Mikhail V Ivanchenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4183510?pdf=render