Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription
Histone tail modifications can greatly influence chromatin-associated processes. Asymmetrically modified nucleosomes exist in multiple cell types, but whether modifications on both sister histones contribute equally to chromatin dynamics remains elusive. Here, we devised a bivalent nucleosome system...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/30178 |