Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription

Histone tail modifications can greatly influence chromatin-associated processes. Asymmetrically modified nucleosomes exist in multiple cell types, but whether modifications on both sister histones contribute equally to chromatin dynamics remains elusive. Here, we devised a bivalent nucleosome system...

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Bibliographic Details
Main Authors: Zhen Zhou, Yu-Ting Liu, Li Ma, Ting Gong, Ya-Nan Hu, Hong-Tao Li, Chen Cai, Ling-Li Zhang, Gang Wei, Jin-Qiu Zhou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/30178