The effect of Ocimum basilicum total extract on the development of tolerance to morphine analgesia in male rats

Background and objectives: Long-term exposure to opiates induces tolerance to the analgesic effect. The chronic use of opioids in glia cells produces pro-inflammatory mediators such as Tissue Necrosis Factor α and interleukins. Regarding the reports on Ocimum basilicum (Family: Lamiaceae) which has...

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Bibliographic Details
Format: Article
Language:English
Published: Iranian Society of Pharmacognosy 2017-11-01
Series:Research Journal of Pharmacognosy
Subjects:
Online Access:http://www.rjpharmacognosy.ir/article_53307_5a89580503c401326468976b6f3c74e2.pdf