HIV Tat-Mediated Induction of Monocyte Transmigration Across the Blood–Brain Barrier: Role of Chemokine Receptor CXCR3

HIV Tat-Mediated Induction of Monocyte Transmigration Across the Blood–Brain Barrier: Role of Chemokine Receptor CXCR3

HIV trans-activator of transcription (Tat), one of the cytotoxic proteins secreted from HIV-infected cells, is also known to facilitate chemokine-mediated transmigration of monocytes into the brain leading, in turn, to neuroinflammation and thereby contributing to the development of HIV-associated n...

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Bibliographic Details
Main Authors: Fang Niu, Ke Liao, Guoku Hu, Shamsudheen Moidunny, Sabita Roy, Shilpa Buch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
monocytes
CXCR3
HIV Tat
BBB
transmigration
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.724970/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.724970/full

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