FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State

FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State

Cancer stem cells (CSCs) are located in dedicated niches, where they remain inert to chemotherapeutic drugs and drive metastasis. Although plasticity in the CSC pool is well appreciated, the molecular mechanisms implicated in the regulation of cancer stemness are still elusive. Here, we define a fuc...

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Bibliographic Details
Main Authors: Athanasios Blanas, Anouk Zaal, Irene van der Haar Àvila, Maxime Kempers, Laura Kruijssen, Mike de Kok, Marko A. Popovic, Joost C. van der Horst, Sandra J. van Vliet
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
glycosylation
fucosylation
colon cancer
pluripotency
stem cells
drug resistance
Online Access:https://www.mdpi.com/2072-6694/12/9/2580

Internet

https://www.mdpi.com/2072-6694/12/9/2580

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