The influence of sleep deprivation and obesity on DNA damage in female Zucker rats

The influence of sleep deprivation and obesity on DNA damage in female Zucker rats

OBJECTIVE: The aim of this study was to evaluate overall genetic damage induced by total sleep deprivation in obese, female Zucker rats of differing ages. METHOD: Lean and obese Zucker rats at 3, 6, and 15 months old were randomly distributed into two groups for each age group: home-cage control and...

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Bibliographic Details
Main Authors: Neuli M. Tenorio, Daniel A. Ribeiro, Tathiana A. Alvarenga, Ana Carolina C. Fracalossi, Viviane Carlin, Camila Hirotsu, Sergio Tufik, Monica L. Andersen
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2013-01-01
Series:Clinics
Subjects:
Sleep Deprivation
Obesity
Zucker Rats
DNA Damage
Comet Assay
Gentle Handling
Female
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000300017

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000300017

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