Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties

Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties

Characterization of non-neoplastic and malignant human stem cell populations in their native state can provide new insights into gliomagenesis. Here we developed a purification strategy to directly isolate EGFR+/− populations from human germinal matrix (GM) and adult subventricular zone autopsy tiss...

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Bibliographic Details
Main Authors: Jessica Tome-Garcia, Rut Tejero, German Nudelman, Raymund L. Yong, Robert Sebra, Huaien Wang, Mary Fowkes, Margret Magid, Martin Walsh, Violeta Silva-Vargas, Elena Zaslavsky, Roland H. Friedel, Fiona Doetsch, Nadejda M. Tsankova
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Reports
Subjects:
neural stem cells
glioma stem cells
germinal matrix
glioblastoma
tumor initiation
neurosphere
FACS
RNA-seq
transcriptome
EGFR
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111730125X

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http://www.sciencedirect.com/science/article/pii/S221367111730125X

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