Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

Bioactive Dietary VDR Ligands Regulate Genes Encoding Biomarkers of Skin Repair That Are Associated with Risk for Psoriasis

Treatment with 1,25-dihydroxyvitamin D3 (1,25D) improves psoriasis symptoms, possibly by inducing the expression of late cornified envelope (LCE)3 genes involved in skin repair. In psoriasis patients, the majority of whom harbor genomic deletion of LCE3B and LCE3C (LCE3C_LCE3B-del), we propose that...

Full description

Bibliographic Details
Main Authors: Amitis Karrys, Islam Rady, Roxane-Cherille N. Chamcheu, Marya S. Sabir, Sanchita Mallick, Jean Christopher Chamcheu, Peter W. Jurutka, Mark R. Haussler, G. Kerr Whitfield
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Nutrients
Subjects:
vitamin D receptor
late cornified envelope genes
docosahexaenoic acid
curcumin
epidermis
keratinocytes
psoriasis treatment
nutraceuticals
differentiation
activator protein-1
Online Access:http://www.mdpi.com/2072-6643/10/2/174

Internet

http://www.mdpi.com/2072-6643/10/2/174

Similar Items