Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson’s disease

Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson’s disease

<p>Abstract</p> <p>Background</p> <p>Parkinson's disease (PD) is a multifactorial disease where environmental factors act on genetically predisposed individuals. Although only 5% of PD manifestations are associated with specific mutations, majority of PD cases are...

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Bibliographic Details
Main Authors: Desplats Paula, Patel Pruthul, Kosberg Kori, Mante Michael, Patrick Christina, Rockenstein Edward, Fujita Masayo, Hashimoto Makoto, Masliah Eliezer
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Molecular Neurodegeneration
Subjects:
Adult neurogenesis
Parkinson’s disease
Maneb
Paraquat
Pesticides
Environmental exposure
Gene expression
Gene x environment interactions
Online Access:http://www.molecularneurodegeneration.com/content/7/1/49

Internet

http://www.molecularneurodegeneration.com/content/7/1/49

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