Stachys sieboldii Extract Supplementation Attenuates Memory Deficits by Modulating BDNF-CREB and Its Downstream Molecules, in Animal Models of Memory Impairment

Stachys sieboldii Extract Supplementation Attenuates Memory Deficits by Modulating BDNF-CREB and Its Downstream Molecules, in Animal Models of Memory Impairment

Cholinergic dysfunction, impaired brain-derived neurotrophic factor and cAMP response element binding protein (BDNF-CREB) signaling are one of the major pathological hallmarks of cognitive impairment. Therefore, improving cholinergic neurotransmission, and regulating the BDNF-CREB pathway by downreg...

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Bibliographic Details
Main Authors: Vijaya Abinaya Ravichandran, Mina Kim, Seong Kyu Han, Youn Soo Cha
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Nutrients
Subjects:
Stachys sieboldii
dementia
memory loss
cholinergic neurotransmission
neuroplasticity targets
GABAA receptor
Online Access:http://www.mdpi.com/2072-6643/10/7/917

Internet

http://www.mdpi.com/2072-6643/10/7/917

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