Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses

Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses

Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many bioinformatic tools on consensus sequence construction has precluded a thorough analysis of intra-host diversity. To take full advantage of the resoluti...

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Bibliographic Details
Main Authors: Keylie M. Gibson, Margaret C. Steiner, Uzma Rentia, Matthew L. Bendall, Marcos Pérez-Losada, Keith A. Crandall
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
bioinformatics
validation
simulation
viruses
consensus
haplotypes
Online Access:https://www.mdpi.com/1999-4915/12/7/758

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https://www.mdpi.com/1999-4915/12/7/758

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