Deep learning for diagnosis of acute promyelocytic leukemia via recognition of genomically imprinted morphologic features

Abstract Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), classified by a translocation between chromosomes 15 and 17 [t(15;17)], that is considered a true oncologic emergency though appropriate therapy is considered curative. Therapy is often initiated on clinical su...

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Bibliographic Details
Main Authors: John-William Sidhom, Ingharan J. Siddarthan, Bo-Shiun Lai, Adam Luo, Bryan C. Hambley, Jennifer Bynum, Amy S. Duffield, Michael B. Streiff, Alison R. Moliterno, Philip Imus, Christian B. Gocke, Lukasz P. Gondek, Amy E. DeZern, Alexander S. Baras, Thomas Kickler, Mark J. Levis, Eugene Shenderov
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00179-y