Role of Oxidative Stress and the Identification of Biomarkers Associated With Thyroid Dysfunction in Schizophrenics

Role of Oxidative Stress and the Identification of Biomarkers Associated With Thyroid Dysfunction in Schizophrenics

Background: Schizophrenia is associated with a deficiency of dietary antioxidants like vitamin B6, B9, and B12 resulting in defective methylation leading to hyperhomocysteinemia. Hyperhomocysteinemia causes mitochondrial DNA damage, oxidative stress, vascular damage, and lipid peroxidation. Oxidativ...

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Bibliographic Details
Main Authors: Mahmood Rasool, Arif Malik, Shamaila Saleem, Muhammad Abdul Basit Ashraf, Altaf Qadir Khan, Sulayman Waquar, Ayesha Zahid, Sumaira Shaheen, Muhammad Abu-Elmagd, Kalamegam Gauthaman, Peter Natesan Pushparaj
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
schizophrenia
hyperhomocysteinemia
oxidative stress
autoimmune thyroid diseases
biomarkers
antioxidants
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.646287/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.646287/full

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