Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome.

Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome.

The aim of this study was to determine the prevalence of MCPyV in Merkel cell carcinoma (MCC) primaries versus lymph node metastasis and to evaluate possible prognostic factors.Samples of MCC primaries and lymph node metastases were stained immunohistochemically for the MCPyV large T-antigen and exp...

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Bibliographic Details
Main Authors: Georg Haymerle, Stefan Janik, Alexandra Fochtmann, Johannes Pammer, Helga Schachner, Lucas Nemec, Michael Mildner, Roland Houben, Matthaeus Ch Grasl, Boban M Erovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5538748?pdf=render

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http://europepmc.org/articles/PMC5538748?pdf=render

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