Terminal differentiation into adipocyte and growth inhibition by PPARγ activation in human A549 lung adenocarcinoma cells

The present study investigated the terminal differentiation capacity into adipocytes and subsequent growth inhibition in A549 cancer cells treated with pioglitazone (PGZ), a PPARγ activator. The rate of cell growth in A549 cells was significantly (P < .05) inhibited in concentrations above 10 μM...

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Main Authors: Dae-Young Kim, Sun-Ha Moon, Jang-Ho Han, Mi-Jeong Kim, Seong-Ju Oh, Dinesh Bharti, Sung-Ho Lee, Jong-Kuen Park, Gyu-Jin Rho, Byeong-Gyun Jeon
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2020.1847731