Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coli

<p>Abstract</p> <p>Background</p> <p>Oncolytic adenoviruses are promising agents for the multimodal treatment of cancer. However, tumor-selectivity is crucial for their applicability in patients. Recent studies by several groups demonstrated that oncolytic adenoviruses...

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Bibliographic Details
Main Authors: Wildner Oliver, Hoffmann Dennis
Format: Article
Language:English
Published: BMC 2006-08-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/36