Association of NR1I2 gene polymorphisms and time of progression to AIDS

Association of NR1I2 gene polymorphisms and time of progression to AIDS

BACKGROUND The time of progression towards AIDS can vary greatly among seropositive patients, and may be associated with host genetic variation. The NR1I2 (PXR) gene, a ligand-activated transcription factor, regulates the transcription immune pathway genes and can therefore be targets of viral repl...

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Bibliographic Details
Main Authors: Rúbia Marília de Medeiros, Carolina Fialho Menti, Jéssica Louise Benelli, Maria Cristina Cotta Matte, Marineide Gonçalves de Melo, Sabrina Esteves de Matos Almeida, Marilu Fiegenbaum
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
AIDS progression
genetic polymorphisms
nuclear receptors
NR1I2
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000400269&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000400269&lng=en&tlng=en

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