Central masked adjudication of stroke diagnosis at trial entry offered no advantage over diagnosis by local clinicians: Secondary analysis and simulation

Background: Central adjudication of stroke type is commonly implemented in large multicentre clinical trials. We investigated the effect of central adjudication of diagnosis of stroke type at trial entry in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. Methods: ENOS recruited patients with ac...

Full description

Bibliographic Details
Main Authors: Peter J. Godolphin, Trish Hepburn, Nikola Sprigg, Liz Walker, Eivind Berge, Ronan Collins, John Gommans, George Ntaios, Stuart Pocock, Kameshwar Prasad, Joanna M. Wardlaw, Philip M. Bath, Alan A. Montgomery
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865418301170