Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences

Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences

Coronavirus disease 2019 (COVID-19) has caused massive disruptions to society and the economy, and the transcriptional regulatory mechanisms behind the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are poorly understood. Herein, we determined the crystal structure of the SARS-CoV-2 nu...

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Bibliographic Details
Main Authors: Mei Yang, Suhua He, Xiaoxue Chen, Zhaoxia Huang, Ziliang Zhou, Zhechong Zhou, Qiuyue Chen, Shoudeng Chen, Sisi Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Chemistry
Subjects:
COVID-19
coronavirus
SARS-CoV-2
nucleocapsid protein
C terminal domain
crystal structure
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.624765/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2020.624765/full

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