Following mitochondrial footprints through a long mucosal path to lung cancer.

BACKGROUND:Mitochondrial DNA (mtDNA) mutations are reported in different tumors. However, there is no information on the temporal development of the mtDNA mutations/content alteration and their extent in normal and abnormal mucosa continuously exposed to tobacco smoke in lung cancer patients. METHOD...

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Bibliographic Details
Main Authors: Santanu Dasgupta, Rex C Yung, William H Westra, David A Rini, Johann Brandes, David Sidransky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2719062?pdf=render