An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation.

An Extended, Boolean Model of the Septation Initiation Network in S.Pombe Provides Insights into Its Regulation.

Cytokinesis in fission yeast is controlled by the Septation Initiation Network (SIN), a protein kinase signaling network using the spindle pole body as scaffold. In order to describe the qualitative behavior of the system and predict unknown mutant behaviors we decided to adopt a Boolean modeling ap...

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Bibliographic Details
Main Authors: Anastasia Chasapi, Paulina Wachowicz, Anne Niknejad, Philippe Collin, Andrea Krapp, Elena Cano, Viesturs Simanis, Ioannis Xenarios
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4526654?pdf=render

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http://europepmc.org/articles/PMC4526654?pdf=render

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