HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells

HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells

Heat Shock Protein A2 (HSPA2) is a member of the HSPA (HSP70) chaperone family and has a critical role for male fertility. HSPA2 is present in a number of somatic organs. Limited evidence suggests that HSPA2 may be involved in regulating epithelial cell differentiation. HSPA2 also emerged as a cance...

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Bibliographic Details
Main Authors: Damian Robert Sojka, Agnieszka Gogler-Pigłowska, Katarzyna Klarzyńska, Marta Klimczak, Alicja Zylicz, Magdalena Głowala-Kosińska, Zdzisław Krawczyk, Dorota Scieglinska
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
HSPA2
HSP70
heat shock protein
bronchial epithelial cells
non-small cell lung carcinoma
breast cancer
Online Access:https://www.mdpi.com/2072-6694/12/10/2749

Internet

https://www.mdpi.com/2072-6694/12/10/2749

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