Aerosol-induced brucellosis increases TLR-2 expression and increased complexity in the microanatomy of astroglia in rhesus macaques

Aerosol-induced brucellosis increases TLR-2 expression and increased complexity in the microanatomy of astroglia in rhesus macaques

Brucella melitensis, a bacterial pathogen and agent of epizootic abortion causes multiple pathologies in humans as well as a number of agriculturally important animal species. Clinical human brucellosis manifests as a nonspecific, chronic debilitating disease characterized by undulant fever, arthrop...

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Bibliographic Details
Main Authors: Kim M Lee, Kevin B Chiu, Hope A Sansing, Peter J Didier, Thomas A Ficht, Angela M Arenas-Gamboa, Chad J Roy, Andrew G MacLean
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Brucella
Gliosis
astrocyte
Toll-like receptor
innate immune activation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00086/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00086/full

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