Comparative molecular cell-of-origin classification of diffuse large B-cell lymphoma based on liquid and tissue biopsies

Comparative molecular cell-of-origin classification of diffuse large B-cell lymphoma based on liquid and tissue biopsies

Abstract Background Diffuse large B-cell lymphoma (DLBCL) is a heterogenous blood cancer, but can be broadly classified into two main subtypes, germinal center B-cell-like (GCB) and activated B-cell-like (ABC). GCB and ABC subtypes have very different clinical courses, with ABC having a much worse s...

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Bibliographic Details
Main Authors: Ewan Hunter, Ronald McCord, Aroul S. Ramadass, Jayne Green, Jurjen W. Westra, Kirsten Mundt, Alexandre Akoulitchev
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Translational Medicine Communications
Subjects:
Diffuse large B-cell lymphoma (DLBCL)
Disease subtype
Epigenetics
Gene expression
Chromatin conformation signatures (CCS)
Online Access:http://link.springer.com/article/10.1186/s41231-020-00054-1

Internet

http://link.springer.com/article/10.1186/s41231-020-00054-1

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