Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice

Early-Life Human Microbiota Associated With Childhood Allergy Promotes the T Helper 17 Axis in Mice

The intestinal microbiota influences immune maturation during childhood, and is implicated in early-life allergy development. However, to directly study intestinal microbes and gut immune responses in infants is difficult. To investigate how different types of early-life gut microbiota affect immune...

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Bibliographic Details
Main Authors: Dagbjort H. Petursdottir, Sofia Nordlander, Khaleda Rahman Qazi, Claudia Carvalho-Queiroz, Omneya Ahmed Osman, Eva Hell, Sophia Björkander, Yeneneh Haileselassie, Marit Navis, Efthymia Kokkinou, Ivan Zong Long Lio, Julia Hennemann, Björn Brodin, Douglas L. Huseby, Caroline Nilsson, Diarmaid Hughes, Klas I. Udekwu, Eva Sverremark-Ekström
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
infant microbiota
allergic heredity
immune development
germ-free
T helper 17-responses
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01699/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01699/full

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