Where Metabolism Meets Senescence: Focus on Endothelial Cells

Despite the decline in their proliferative potential, senescent cells display a high metabolic activity. Senescent cells have been shown to acquire a more glycolytic state even in presence of high oxygen levels, in a way similar to cancer cells. The diversion of pyruvate, the final product of glycol...

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Bibliographic Details
Main Authors: Jacopo Sabbatinelli, Francesco Prattichizzo, Fabiola Olivieri, Antonio Domenico Procopio, Maria Rita Rippo, Angelica Giuliani
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01523/full