Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids

Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids

Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from Archaea to humans. It has been reported that fibrillarin is involved in the methylation of histone H2A in nucleoli and other processes, including viral progression, cellular...

Full description

Bibliographic Details
Main Authors: Francisco Guillen-Chable, Ulises Rodríguez Corona, Alejandro Pereira-Santana, Andrea Bayona, Luis Carlos Rodríguez-Zapata, Cecilia Aquino, Lenka Šebestová, Nicolas Vitale, Pavel Hozak, Enrique Castano
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
nucleolus
ribonucleolar particle
rRNA
fibrillarin
phosphoinositides
viral progression
Online Access:https://www.mdpi.com/2073-4409/9/5/1143

Internet

https://www.mdpi.com/2073-4409/9/5/1143

Similar Items