Biochemical complexity drives log-normal variation in genetic expression
Cells exhibit a high degree of variation in levels of gene expression, even within otherwise homogeneous populations. The standard model to describe this variation centres on a gamma distribution driven by stochastic bursts of translation. Stochastic bursting, however, cannot account for the well-es...
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| Format: | Article |
| Language: | English |
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Wiley
2017-07-01
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| Series: | Engineering Biology |
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| Online Access: | https://digital-library.theiet.org/content/journals/10.1049/enb.2017.0004 |