Epithelial Bone Morphogenic Protein 2 and 4 Are Indispensable for Tooth Development

The Bmp2 and Bmp4 expressed in root mesenchyme were essential for the patterning and cellular differentiation of tooth root. The role of the epithelium-derived Bmps in tooth root development, however, had not been reported. In this study, we found that the double abrogation of Bmp2 and Bmp4 from mou...

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Bibliographic Details
Main Authors: Haibin Mu, Xin Liu, Shuoshuo Geng, Dian Su, Heran Chang, Lili Li, Han Jin, Xiumei Wang, Ying Li, Bin Zhang, Xiaohua Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.660644/full