Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli

Abstract Background Polynucleotide phosphorylase (PNPase, encoded by pnp) is generally thought of as an enzyme dedicated to RNA metabolism. The pleiotropic effects of PNPase deficiency is imputed to altered processing and turnover of mRNAs and small RNAs, which in turn leads to aberrant gene express...

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Bibliographic Details
Main Authors: Thomas Carzaniga, Giulia Sbarufatti, Federica Briani, Gianni Dehò
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Microbiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12866-017-0980-z