Sex-Dependent Effects of 7,8-Dihydroxyflavone on Metabolic Health Are Associated with Alterations in the Host Gut Microbiome

Sex-Dependent Effects of 7,8-Dihydroxyflavone on Metabolic Health Are Associated with Alterations in the Host Gut Microbiome

7,8-Dihydroxyflavone (DHF) is a naturally occurring flavonoid that has been reported to protect against a variety of pathologies. Chronic administration of DHF prevents high-fat diet (HFD)-induced obesity in female, but not male, mice. However, the mechanisms underlying this sexual dimorphism have n...

Full description

Bibliographic Details
Main Authors: Priyanka Sharma, Guojun Wu, Deeptha Kumaraswamy, Natalie Burchat, Hong Ye, Yongjia Gong, Liping Zhao, Yan Y. Lam, Harini Sampath
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Nutrients
Subjects:
metabolic syndrome
intestinal microbiome
dysbiosis
polyphenols
sex differences
Online Access:https://www.mdpi.com/2072-6643/13/2/637

Internet

https://www.mdpi.com/2072-6643/13/2/637

Similar Items