Transcriptome analysis of newt lens regeneration reveals distinct gradients in gene expression patterns.

Regeneration of the lens in newts is quite a unique process. The lens is removed in its entirety and regeneration ensues from the pigment epithelial cells of the dorsal iris via transdifferentiation. The same type of cells from the ventral iris are not capable of regenerating a lens. It is, thus, ex...

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Bibliographic Details
Main Authors: Konstantinos Sousounis, Mario Looso, Nobuyasu Maki, Clifford J Ivester, Thomas Braun, Panagiotis A Tsonis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3628982?pdf=render