Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of upper and lower motor neurons. There is a need for an imaging biomarker to track disease progression. Previously, magnetic resonance imaging (MRI) has shown loss of grey and white matter i...

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Bibliographic Details
Main Authors: Ashwag R. Alruwaili, Kerstin Pannek, Robert D. Henderson, Marcus Gray, Nyoman D. Kurniawan, Pamela A. McCombe
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Medical Imaging
Subjects:
ALS
MND
DTI
Online Access:http://link.springer.com/article/10.1186/s12880-020-00489-w