Serial MRI studies over 12 months using manual and atlas-based region of interest in patients with amyotrophic lateral sclerosis
Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of upper and lower motor neurons. There is a need for an imaging biomarker to track disease progression. Previously, magnetic resonance imaging (MRI) has shown loss of grey and white matter i...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | BMC Medical Imaging |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12880-020-00489-w |