Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation.

Silibinin inhibits HIV-1 infection by reducing cellular activation and proliferation.

Purified silymarin-derived natural products from the milk thistle plant (Silybum marianum) block hepatitis C virus (HCV) infection and inhibit T cell proliferation in vitro. An intravenous formulation of silibinin (SIL), a major component of silymarin, displays anti-HCV effects in humans and also in...

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Bibliographic Details
Main Authors: Janela McClure, Erica S Lovelace, Shokrollah Elahi, Nicholas J Maurice, Jessica Wagoner, Joan Dragavon, John E Mittler, Zane Kraft, Leonidas Stamatatos, Helen Horton, Stephen C De Rosa, Robert W Coombs, Stephen J Polyak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3404953?pdf=render

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http://europepmc.org/articles/PMC3404953?pdf=render

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