Global impact of somatic structural variation on the DNA methylome of human cancers

Global impact of somatic structural variation on the DNA methylome of human cancers

Abstract Background Genomic rearrangements exert a heavy influence on the molecular landscape of cancer. New analytical approaches integrating somatic structural variants (SSVs) with altered gene features represent a framework by which we can assign global significance to a core set of genes, analog...

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Bibliographic Details
Main Authors: Yiqun Zhang, Lixing Yang, Melanie Kucherlapati, Angela Hadjipanayis, Angeliki Pantazi, Christopher A. Bristow, Eunjung Alice Lee, Harshad S. Mahadeshwar, Jiabin Tang, Jianhua Zhang, Sahil Seth, Semin Lee, Xiaojia Ren, Xingzhi Song, Huandong Sun, Jonathan Seidman, Lovelace J. Luquette, Ruibin Xi, Lynda Chin, Alexei Protopopov, Peter J. Park, Raju Kucherlapati, Chad J. Creighton
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1818-9

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http://link.springer.com/article/10.1186/s13059-019-1818-9

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