Duplex Reverse-Hybridization Assay for The Simultaneous Detection of KRAS/BRAF Mutations in FFPE-extracted Genomic DNA from Colorectal Cancer Specimens

We report the performance evaluation of a non-quantitative reverse-hybridization assay (KRAS-BRAF StripAssay) designed for the simultaneous detection of 10 mutations in codons 12 and 13 of the KRAS gene and BRAF mutation V600E. Dilution experiments using DNA from tumor cell lines or from formalin-fi...

Full description

Bibliographic Details
Main Authors: Veronika Buxhofer-Ausch, Christoph Ausch, Robert Zeillinger, Christian Oberkanins, Nadia Dandachi, Angelika Reiner-Concin, Gernot Kriegshäuser
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-120960