C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells

C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells

Oncolytic virus (OV) therapy is widely considered as a major breakthrough in anti-cancer treatments. In our previous study, the efficacy and safety of using C-REV for anti-cancer therapy in patients during stage I clinical trial was reported. The stimulator of interferon genes (STING)–TBK1–IRF3–IFN...

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Bibliographic Details
Main Authors: Daishi Morimoto, Shigeru Matsumura, Itzel Bustos-Villalobos, Patricia Angela Sibal, Toru Ichinose, Yoshinori Naoe, Ibrahim Ragab Eissa, Mohamed Abdelmoneim, Nobuaki Mukoyama, Noriyuki Miyajima, Maki Tanaka, Yasuhiro Kodera, Hideki Kasuya
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
oncolytic virus
cGAS–STING pathway
human pancreatic cancer cell lines
Online Access:https://www.mdpi.com/2073-4409/10/6/1502

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https://www.mdpi.com/2073-4409/10/6/1502

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