Anti-herpes simplex virus activity of n-docosanol correlates with intracellular metabolic conversion of the drug

The 22-carbon fatty alcohol, n-docosanol, exhibits in vitro antiviral activity against several lipid-enveloped viruses including herpes simplex viruses 1 and 2 by a mechanism that interferes with normal viral entry into target cells. We previously reported that mammalian cells incorporate significan...

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Bibliographic Details
Main Authors: L E Pope, J F Marcelletti, L R Katz, D H Katz
Format: Article
Language:English
Published: Elsevier 1996-10-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520372990