Placental extract suppresses cardiac hypertrophy and fibrosis in an angiotensin II-induced cachexia model in mice

Placental extract suppresses cardiac hypertrophy and fibrosis in an angiotensin II-induced cachexia model in mice

Cachexia is an intractable metabolic disorder that causes extreme weight loss. It is a symptom of many chronic diseases, including cancer, liver failure, congestive heart failure and chronic kidney disease, and there is as yet no effective treatment. While the mechanisms underlying cachexia are comp...

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Bibliographic Details
Main Authors: Akihiro Yamauchi, Akiko Kamiyoshi, Takayuki Sakurai, Hiroyuki Miyazaki, Eiichi Hirano, Hong Seok Lim, Taiichi Kaku, Takayuki Shindo
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Heliyon
Subjects:
Biochemistry
Cardiac hypertrophy
Human placenta extract
Cardiac fibrosis
Angiotensin II
Cachexia
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019363157

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http://www.sciencedirect.com/science/article/pii/S2405844019363157

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