Reciprocal interference between the NRF2 and LPS signaling pathways on the immune‐metabolic phenotype of peritoneal macrophages

Reciprocal interference between the NRF2 and LPS signaling pathways on the immune‐metabolic phenotype of peritoneal macrophages

Abstract The metabolic and immune adaptation to extracellular signals allows macrophages to carry out specialized functions involved in immune protection and tissue homeostasis. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a transcription factor that coordinates cell redox and metabolic res...

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Bibliographic Details
Main Authors: Federica Mornata, Giovanna Pepe, Chiara Sfogliarini, Electra Brunialti, Gianenrico Rovati, Massimo Locati, Adriana Maggi, Elisabetta Vegeto
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Pharmacology Research & Perspectives
Subjects:
immunometabolism
inflammation
NFκB
NRF2
resident macrophages
Online Access:https://doi.org/10.1002/prp2.638

Internet

https://doi.org/10.1002/prp2.638

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